Check out this great video from Philip Arthur Moore
http://s0.videopress.com/player.swf?v=1.03
In the video he talks about a few major approaches to creating WordPress themes:
- Parent and child themes
- Theme frameworks
- Starter themes
- From scratch
You can also find a nice write up he did of the content over on the Codepoet blog.
He also has his slides from the talk up on slideshare
WordPress Educator Zac Gordon 
I’m getting very near the point where having my own boilerplate theme would be useful as a jumping off point. I know that the Automattic team likes _s, but I find it a lot easier (and to me at least, cleaner) to use Starkers as a blank theme.
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Let me know when you have it! I’ll do a little review and promotion for you!
I’m a long time fan of Stalkers too 🙂
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